Atrial Fibrillation and Sudden Cardiac Death

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منابع مشابه

Atrial Fibrillation and Sudden Cardiac Death

Several recent observational studies have shown an association between AF and SCD. In the Cardiovascular Health Study, the unadjusted incidence of SCD was 12 per 1,000 person-years in those with AF versus 3.8 per 1,000 person years in those without AF. Following adjustment, AF remained associated with an increased hazard of SCD (hazard ratio [HR]: 2.14 [95% confidence interval (CI): 1.60 to 2.8...

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Mutation in Nuclear Pore Component NUP155 Leads to Atrial Fibrillation and Early Sudden Cardiac Death

Atrial fibrillation (AF) is the most common form of sustained clinical arrhythmia. We previously mapped an AF locus to chromosome 5p13 in an AF family with sudden death in early childhood. Here we show that the specific AF gene underlying this linkage is NUP155, which encodes a member of the nucleoporins, the components of the nuclear pore complex (NPC). We have identified a homozygous mutation...

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Pathophysiologic observations in prehospital ventricular fibrillation and sudden cardiac death.

In order to better understand the problem of prehospital sudden cardiac death (SCD) two groups of individuals were studied. One group was monitored by rescue squads during attempted rescue. These subjects were defibrillated from prehospital ventricular fibrillation (VF) and hospitalized if they survived or autopsied if they could not be resuscitated. The second group were SCDs which were witnes...

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Predictors of sudden cardiac death in atrial fibrillation: The Atherosclerosis Risk in Communities (ARIC) study

We previously reported that incident atrial fibrillation (AF) is associated with an increased risk of sudden cardiac death (SCD) in the general population. We now aimed to identify predictors of SCD in persons with AF from the Atherosclerosis Risk in Communities (ARIC) study, a community-based cohort study. We included all participants who attended visit 1 (1987-89) and had no prior AF (n = 14,...

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Sudden Cardiac Death in Patients With Atrial Fibrillation: Insights From the ENGAGE AF‐TIMI 48 Trial

BACKGROUND Recent findings suggest that atrial fibrillation is associated with sudden cardiac death (SCD). We examined the incidence, characteristics, and factors associated with SCD in patients with atrial fibrillation. METHODS AND RESULTS SCD was defined as witnessed death ≤60 minutes from the onset of new symptoms or unwitnessed death 1 to 24 hours after being observed alive, without anoth...

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ژورنال

عنوان ژورنال: JACC: Heart Failure

سال: 2014

ISSN: 2213-1779

DOI: 10.1016/j.jchf.2014.03.004